People with "hybrid immunity" are more protected from corona What does this mean?

Two studies published in the Lancet Infectious Diseases journal showed that people who have "hybrid immunity", that is, they received the full vaccine and were infected with corona, enjoy the greatest protection from the virus.

Two new studies show that people who have "hybrid immunity", that is, they received the full vaccine and were infected with Covid-19, have the greatest protection from the Corona virus.

These two studies shed light on the importance of vaccinations for those who have generated natural immunity after recovering from a corona infection they were exposed to.

The two studies, the results of which were published in the Lancet Infectious Diseases journal, stressed the importance of those recovering from the virus receiving corona vaccines.

One of the two studies analyzed the health data of more than 200,000 people in 2020 and 2021 in Brazil, which had the second highest death toll in the world.

And it turned out that the infection provided people who were infected with Covid and received the “Pfizer” or “AstraZeneca” vaccine with 90% protection from hospitalization or death, compared to 81% for the Chinese “Coronavac” vaccine and 58% for the “Johnson & Johnson” vaccine, which is taken as a single dose.

"These four vaccines have proven to provide significant additional protection for those previously infected with Covid-19," said study author Julio Costa from the Federal University of Mato Grosso do Sul.

"Hybrid immunity induced by exposure to natural infection and vaccination will likely become the global standard, and may provide long-term protection against emerging mutants," said Pramod Kumar of the Translational Health Science and Technology Institute in India.

A study based on Sweden's national records up to October 2021 concluded that people who have recovered from Covid maintain a high level of protection against a new infection, up to about 20 months.

And it showed that for people who received two doses of vaccines with hybrid immunity, the risk of infection again decreased by 66% compared to people who only had natural immunity.

Paul Hunter, a professor of medicine at the University of East Anglia who was not involved in the study, told AFP that 20 months of "very good protection is much better than what we would expect from a two-dose vaccine programme."

But he cautioned that the two studies were completed before the "Omicron" mutant became dominant in the world, noting that "it led to a marked decrease in the protection provided by a previous infection."

The results of a study recently published on the medical website medRxiv revealed the protection provided by “hybrid” immunity against “Omicron” and found that 3 doses were effective by 52% of the “Omicron” sub-mutant “BA2”, and the effectiveness rate increased to 77% in the event of infection. previous.

The unreviewed study found that “hybrid immunity resulting from previous infection and enhanced vaccination confers the strongest protection” against the original omicron mutant and its sub-strain.