The study showed that glutathione, a protein found in mulberry leaves, after filtration, significantly improves liver health and reduces the accumulation of fat in it, especially when following a high-fat diet.
In experiments conducted on cells and mice, scientists observed that taking glutathione supplements reduces fat accumulation in the liver, lowers triglyceride and cholesterol levels in the body, and alleviates signs of inflammation and organ damage. In animals on a high-fat diet, this supplement slowed weight gain, improved blood parameters, and reduced the activity of enzymes associated with liver damage.
Further analysis showed that the effect of glutathione is not only related to suppressing inflammatory signaling pathways in the body, but is also related to metabolic restructuring, specifically the production of bile acids and amino acids.
The researchers noted that their findings suggest that glutathione extracted from mulberry leaves can be used as a functional food supplement to treat fatty liver problems and some liver problems caused by obesity, but clinical studies are needed to confirm the benefit of this substance for humans.
The study was published in the journal Food & Function
