Newcastle took the lead through Harvey Barnes in the 86th minute, but Barca equalized late on, UEFA noted.
This draw means that Barcelona and Newcastle must win in the second leg at Camp Nou Stadium, Barcelona, next Wednesday to qualify for the quarter-finals.
Newcastle created the first chance of the game when William Osula's header sailed over the Barca crossbar.
It was Anthony Elanga's turn to threaten Barca's goal, but his movement was stopped by the Blaugrana defense.
Newcastle performed better than Barca, but until half time.
