Scientists from Novosibirsk State Technical University have developed and patented a biodegradable frozen gel that can be used to preserve microorganisms without the need for complex and expensive preservation processes.
According to the university's media office, this frozen gel can be used in many fields, including medicine for targeted drug delivery, the production of nutritional supplements and functional foods, the food industry for storing bacterial starters used in the production of yogurt and fermented dairy products, the biopharmaceutical industry for storing preservable bacterial strains, as well as the agricultural sector for the production of microbiological preparations.
A source in the media office said: "One of the most important advantages of this gel is its ability to maintain the viability of bacteria for long periods at room temperature. This approach is superior to traditional storage methods that often require special thermal conditions. Methods such as freeze-drying and deep-freezing also provide long-term preservation, but they are expensive and consume large amounts of energy."
Anastasia Correll, head of the research team, explained that the gel was developed using a two-stage aldehyde-based manufacturing process, employing a gentle technique that avoids high temperatures and harsh conditions. She added that the modified chitosan reduced the polymer's toxicity to cells, making it safe for intestinal cells.
She said: "The gel does not break down in the acidic environment of the stomach, but rather acts as a protective coating for the bacteria it contains. When it reaches the intestines, where the environment is slightly alkaline, it gradually begins to dissolve, allowing for a prolonged release of bacteria and ensuring targeted delivery of the probiotics."
