During the study, the researchers examined the effects of a standardized saffron extract containing precisely defined amounts of safranal and crocin, the two main active compounds in the plant. They conducted experiments on elderly mice to discover the effects of this extract on memory, increased anxiety, and metabolic disorders. They found that when the extract is added to food, it reaches the bloodstream and leaves beneficial biological effects that affect all of the above.
Scientists have found that high doses of this extract reduce anxiety levels and help the brain recognize new things and information, indicating improved memory function. These changes were accompanied by a reorganization of signaling molecules in the brain associated with stress, emotions, and neuroplasticity.
Researchers have found that low doses of saffron extract helped slow age-related weight loss and affected genes that regulate fat metabolism in the liver.
The researchers pointed out that the results they obtained are based on a study conducted on laboratory animals, so they cannot be relied upon before clinical trials are conducted on humans.
A previous study also indicated that saffron helps reduce inflammation and improve mood in people with Parkinson's disease.
