Research into appetite-regulating hormones is leading the predictions for the 2026 Nobel Prize in Medicine, as the Nobel Prize season kicks off on Monday.
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This comes amid expectations that the prize will honor discoveries that paved the way for the development of weight loss drugs such as "Ozempic" and "Mongaro".
The six Nobel Prizes in the fields of medicine, physics, chemistry, literature, peace and economics will be announced successively between October 5 and 12, starting with the medicine prize, which will be announced at 11:30 a.m. Central European Time (i.e., 12:30 p.m. Mecca time, and 9:30 a.m. GMT).
Nobel Prize observers believe that research on glucagon-like peptide-1 (GLP-1) may be a leading contender. The body releases this hormone in the intestines after eating, and it helps send signals of satiety; drugs like Ozempic mimic its effects.
The competition may also include research into the microbiome, i.e., gut bacteria, along with the discovery of the hormones leptin and ghrelin, which contribute to regulating hunger and satiety.
David Pendlebury, head of research analysis at Clarivate, said that awarding the Nobel Prize for GLP-1 research is a "possible possibility," adding that he puts it at the top of his list of predictions because of its "enormous clinical impact worldwide."
Among the most prominent names in this field are Canadian endocrinologist Daniel Drucker, Danish physician Jens Jørgen Holst, and Yugoslavian-American chemist Svetlana Mojsova.
The nominations are not limited to obesity research, as the Nobel Committee may also honor stem cell research and its role in skin regeneration and wound healing, with Ellen Fox and Fiona Watt being among the most prominent names in this field.
Also noteworthy is the "optical coherence tomography" technique, which uses light to produce accurate images of tissues, especially the retina and optic nerve, helping doctors to detect and monitor diseases.
The projections also include research on "adhesion receptors" in the immune system, linked to the work of American immunologist Timothy Springer, as well as breast cancer research and DNA sequencing technologies that have contributed to the fight against the coronavirus.
Following the medicine prize, the physics prize will be announced on Tuesday, the chemistry prize on Wednesday, and the literature prize on Thursday. Speculation suggests a female writer is likely to win, with names such as Argentinian Samantha Schöpflin, Jamaican Kincaid, Kan Shiwe, and Cristina Rivera Garza among those being mentioned.
All eyes are on the Nobel Peace Prize, which will be announced Friday in Oslo, amid expectations that the committee will look for a winner who enjoys broad consensus after the controversy that accompanied last year's award to Venezuelan opposition leader Maria Corina Machado.
Christian Berg Harbeken, secretary of the Nobel Committee, said that pressure on the committee was normal, adding: "We're quite used to it."
Among the organizations and names being considered this year are Save the Children, along with Sudan's Emergency Response Rooms and the Committee to Protect Journalists.
The Nobel Prize season concludes with the Economics Prize on October 12.
The Nobel Prizes are among the world's most prestigious awards, presented annually to individuals and organizations that have made exceptional contributions to humanity in various fields. The prizes are named after the Swedish scientist and inventor Alfred Nobel, who stipulated in his 1895 will that the bulk of his fortune be used to establish prizes to reward those who have conferred "the greatest benefit on mankind."
The Nobel Prizes were first awarded in 1901. Most of the prizes are announced in Stockholm, while the Nobel Peace Prize is awarded in the Norwegian capital, Oslo.
The winners are chosen by various institutions and committees. The Royal Swedish Academy of Sciences awards the prizes for physics, chemistry, and economics, the Nobel Assembly at the Karolinska Institute selects the winner of the medicine prize, the Swedish Academy takes over the literature prize, and the Norwegian Nobel Committee selects the winner of the peace prize.
The prizes are usually announced in October, while the award ceremony takes place on December 10, the anniversary of Alfred Nobel's death.
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