Unexpected negative consequences of taking sedative-hypnotics Unexpected negative consequences of taking sedative-hypnotics

Unexpected negative consequences of taking sedative-hypnotics

Unexpected negative consequences of taking sedative-hypnotics

Researchers from the University of Hong Kong discovered that taking sedative and hypnotic medications leads to an increased risk of bone fractures.

Sleep Medicine Reviews magazine indicates that researchers studied 20 descriptive (observational) studies conducted by scientists from 11 countries in the world, including six million people.

Scientists isolated information about the health status of study participants and their taking of different medications. The results of a meta-analysis (effect size analysis) of scientific studies showed that participants who take sedative-hypnotics have an increased risk of bone fractures compared to those who do not take them.

It became clear to the researchers that taking these medications increases the risk of hip fractures by 32 percent, and the risk of other bone fractures in the body increases by 41 percent. These percentages are the same if you take these medications, whether for a long or short period.

The researchers indicate that these results may be useful for the elderly, because the density and strength of bones decrease with age and is called (osteoporosis), and taking sedative and hypnotic medications exacerbates osteoporosis. Therefore, they should take it after consulting a doctor.

Britain : Testing “miracle pills” To temporarily prevent pregnancy in men

In Britain, clinical tests have begun for a drug that temporarily stops fertility in men.
According to scientists, a drug called YCT-529 is able to make a man infertile for 3 hours by simply taking one pill, meaning he is unable to fertilize.

As Professor Jonda George from the University of Minnesota explained: which has been studying the problem for the past 20 years, the drug "separates" RAR-alpha protein, as a retinoic acid receptor, is released by the male body. As a result, the testicles stop producing sperm, so how can pregnancy occur without sperm? - Even a slight decrease in their number makes this very difficult to achieve.

That is, YCT-529 does not hinder intercourse, does not harm the body in any way, and semen is eventually ejaculated as usual, but without sperm in it for 3 hours.

According to scientists, the effect of the drug is reversible. If you stop taking the pills, the ability to get pregnant will return after some time.

And this is all that the American biopharmaceutical company YourChoice Therapeutics, manufacturer of the miracle pill, is testing. 16 British volunteers from Nottingham agreed to participate in the clinical trials.

The Daily Mail said: YCT-529 was almost 100% effective when experiments were conducted on mice and monkeys.

The inventors of YCT-529 say that the drug is not hormonal, knowing that hormonal drugs stop the production of testosterone, which is the male sex hormone. As testosterone disappears, you can lose sexual desire.

Skeptics fear that with the advent of the male birth control pill, men and even women will tend not to care about using condoms, which will lead to an increase in the number of sexually transmitted diseases.
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