The Israeli Air Force said in a statement on Wednesday that it "intercepted two hostile drones in the Dead Sea area between 02:20-02:22 and 02:30 local time (3 GMT)."
The statement did not mention the party that launched the two drones, but merely said that they came from the east.
This came shortly after the Israeli military announced in a statement that air raid sirens had been sounded in the Dead Sea area, as a result of "a warning of enemy drones infiltrating the area."
The privately owned Hebrew newspaper Yedioth Ahronoth reported that the drones infiltrated the town of Ein Gedi after coming from Iran via Jordanian airspace.
Since dawn on Friday, Israel has been launching a US-backed military operation against Iran, targeting nuclear facilities and missile bases. The operation has resulted in the deaths of 224 people and the injury of 1,277 others, including military leaders and nuclear scientists, according to Iranian sources.
Tehran responded to the attacks by launching ballistic missiles and drones, killing approximately 24 people and wounding hundreds more inside Israel.
Fears of an escalation in the war are growing, with Western and Israeli reports indicating the possibility of the United States officially joining the operations. This comes after US President Donald Trump's statements on Tuesday calling on Iran to "surrender unconditionally" and hinting at the possibility of targeting Supreme Leader Ali Khamenei.