Mexico City, September 21.- A study by the University of Malaga, Spain, in collaboration with the University of Texas, United States, has identified a new therapeutic approach that could slow Alzheimer's disease by eliminating toxic proteins from the brain, the main cause of neuronal death in the circulatory system.
The researchers discovered the approach based on the brain damage they detected in elderly cattle, which is similar to that observed in the disease. Inés Moreno led this study, which discovered that the aggregation and accumulation of toxic proteins in the brain, such as beta-amyloid and hyperphosphorylated tau, is, at the molecular level, one of the main causes of the development of Alzheimer's, according to the scientist from the Cell Biology Department at the University of Malaga, who led the analysis.
The expert has analyzed the presence of these toxic proteins in the brains of cattle, their similarities to the deposits observed in patients, and their ability to accelerate the progression of the disease.
In his study, Moreno managed to reduce, in a preclinical model, the amount of toxic proteins in the brain by up to 40-80 percent, the University of Malaga reported yesterday in a statement.
