In an exclusive interview with Fox News, Dr. Daniel Amen, the well-known psychiatrist and founder of Amen Clinics in California, revealed his great enthusiasm for using saffron to support mental health.
He said: "I am very fond of saffron, as I am of Lebanese origin, and we use it extensively in Eastern cuisine. There is even a popular saying in Iran that says: If you are happier than usual, you must have eaten saffron."
What makes this plant particularly interesting is the scientific evidence supporting its benefits. Dr. Amin cited research findings that confirmed that a small dose of 30 mg of saffron was "as effective" as traditional antidepressants in randomized controlled trials.
While many traditional antidepressants have a negative impact on sexual function, saffron comes as a pleasant surprise, as Dr. Amin explains: "As a psychiatrist, I don't want to harm the emotional lives of my patients. Research has shown that saffron improves sexual function, unlike traditional medications."
The benefits of saffron aren't limited to improving mood; multiple studies have confirmed its ability to enhance memory and concentration. A recent study published in Reviews in Clinical Medicine in 2025 also revealed saffron's role in significantly alleviating premenstrual syndrome symptoms after 8 to 12 weeks of use.
Further evidence of saffron's effectiveness was provided by researchers who analyzed 192 trials involving over 17,000 patients and 44 different dietary supplements. The striking result was that saffron topped the list as the most effective supplement for combating depression, demonstrating moderate to strong effects.
The analysis reveals the potential to enhance the effectiveness of traditional antidepressants by adding certain supplements. Dr. Amin recommends: "If you are taking an antidepressant and want to improve its results, consider adding zinc and curcumin. Saffron, zinc, and curcumin make a fantastic combination."
To obtain its therapeutic benefits, the amount of saffron used in cooking may not be sufficient, so supplements are available in capsules, tablets, and powders. The recommended dose is 30 mg daily, but experts caution that studies have not yet determined its long-term effects.
It's important to be aware that high doses or prolonged use may cause side effects such as anxiety, changes in appetite, upset stomach, drowsiness, or headaches. Therefore, it's advisable to consult a doctor before starting saffron supplements, especially for those taking other medications or with certain health conditions.
Thus, saffron becomes not just a spice that adds a distinctive flavor to food, but a promising natural element in the world of mental and psychological health, opening new horizons for integrative treatment that combines the best of traditional medicine and natural therapies.