Genes determine the impact of microplastics on the brain: A Russian study reveals the details

 

Genes determine the impact of microplastics on the brain: A Russian study reveals the details

A scientist from Novosibirsk revealed, during experiments she conducted on laboratory animals, that the effect of microplastic particles found in food depends on the individual genetic makeup of the organism.

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This was reported by TASS news agency, citing Natalia Stefanova, a leading researcher at the Laboratory of Molecular Mechanisms of Aging at the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences. She presented this information at the Technoprome-2026 scientific forum, which took place in late August in Western Siberia.

According to previous data obtained by scientists in Vienna, humans ingest approximately 5 grams of microplastic particles per week , equivalent to the weight of a credit card. To study the contribution of environmental factors to longevity, the scientists analyzed the impact of microplastic particles on the aging process of living organisms.

Stefanova said, "The effect of microplastic consumption depends on the genotype, that is, on the characteristics of neurons and glial cells (helper cells in the nervous system) in the brain. It turns out that microplastic consumption affects differently depending on the genotype; there is a scenario for its effect in a healthy organism, while there is another scenario in organisms in which neurodegenerative changes have begun to develop. If microplastic consumption continues, it may accelerate brain aging, and consequently the aging of other organs and systems."

During the experiments, plastic particles were added to the food of two strains of laboratory mice. These particles were made of polyethylene terephthalate, a material used in the manufacture of bottles, containers, and other packaging.

According to Stefanova, healthy animals that ingested microplastic particles showed an inflammatory response, while animals predisposed to Alzheimer's disease showed a redistribution of cells in a brain structure, the hippocampus, which is responsible for memory and learning.

Scientists plan to conduct a detailed study of the internal organs of mice in the future, with the aim of identifying the areas where the largest quantities of microplastic particles have accumulated .

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