Al-Shaif said in a post on the X platform: "As a result of the Zionist aggression on Sana'a International Airport and the resulting extensive damage, it has been decided to suspend all flights to and from the airport until further notice."
On Tuesday, seven people were killed and 74 others injured in US-Israeli airstrikes on vital sites in Yemen, according to the Houthi group.
The group indicated that the attacks targeted Sanaa International Airport, power stations, and industrial facilities in Sanaa and Amran, in addition to the port of Hodeidah on the Red Sea.
This is the second Israeli attack on Yemen, following the Houthis' targeting of Ben Gurion Airport on Sunday, which injured eight people and prompted 12 international airlines to suspend flights.
On Sunday evening, Israeli Prime Minister Benjamin Netanyahu threatened to launch attacks on Yemen after the Houthi group bombed Ben Gurion Airport.
The Houthi group has repeatedly claimed to have launched ballistic missiles at Ben Gurion Airport, but for the first time, Israel has acknowledged that a Yemeni missile fell near the airport and directly impacted air traffic.
The escalation comes at a time when the Houthi group has been subjected to intense US aggression since mid-March, targeting dozens of sites and resulting in the deaths and injuries of hundreds of civilians. According to the group, Washington has launched 1,300 airstrikes and naval bombardments on Yemen since then.
Despite the resumption of US airstrikes against Yemen following President Donald Trump's orders for the military to launch a "major offensive" against the Houthis, the group continues to carry out military operations targeting targets in Israel and US targets in the Red Sea.