All eyes are on Wednesday as the winner of the Nobel Prize in Chemistry is announced, amid speculation about which scientists and research may receive this honor, including research related to regulating sleep and appetite and gene editing.
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The Royal Swedish Academy of Sciences in Stockholm will announce the name of the winner or winners at 11:45 a.m. local time, which is 09:45 GMT and 12:45 p.m. Mecca time.
Among the potential candidates are researchers who have contributed to the development of our understanding of glucagon-like peptide-1 (GLP-1), a hormone that regulates hunger and is used in weight-loss medications such as Wegovi and Mongaro. Prominent names in this field include Canadian Daniel Drucker, Dane Jens Juul Holst, and Yugoslavian-American Svetlana Mogčová.
The data analytics firm Clarivate also points to research on self-assembling monolayers (SAMs), which are molecular-level coatings used to control surface properties. Among the most prominent names associated with this field are Americans David Allara and Ralph Nuzzo.
Solar cell research also stands out, which David Pendleberry, head of research analysis at Clarivate, believes has been overdue for the Nobel Prize, with Swiss chemist of German origin Michael Grätzel being one of the leading candidates.
In the field of gene editing, the name of American chemist and biologist David Liu stands out. He developed techniques that allow for precise DNA editing within living cells. Lars Broström, science editor at Swedish Radio (Sveriges Radio), considers Liu a leading candidate for the prize.
Speculation also includes French sleep researcher Emmanuel Mignot and Japanese-American biologist Masashi Yanagisawa, in recognition of their research on orexin, a neurotransmitter that plays a key role in regulating sleep and wakefulness.
Other names being put forward include Frenchman Jean-Marie Tarascon for his research in battery technology, Taiwanese-American Chi-Hui Wong for his research in the manufacture of complex carbohydrates and glycoproteins, and American Robert Langer for his research in drug delivery systems and tissue engineering.
The 2025 Nobel Prize in Chemistry was awarded to Susumu Kitagawa of Japan, Richard Robson of Britain, and Omar Yaghi of Jordan , in recognition of their development of "metal-organic frameworks," porous materials that can be used in fields including gas storage, carbon dioxide capture, and water harvesting from the air.
The chemistry prize comes after the physics prize, announced on Tuesday, which was awarded to Belgian physicist Francis Halzen in recognition of his contributions to neutrino research.
The Nobel Prize in Literature will be announced on Thursday, the Nobel Peace Prize on Friday, and the Nobel Economics Prize will conclude the Nobel season on October 12.
The Nobel Prize includes a diploma, a gold medal, and a cash reward of 12 million Swedish kronor, or about $1.2 million. The reward is divided between the winners if the prize is shared.
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